Thursday, May 15, 2014

Sir James Paget and Paget’s disease

Paget's disease was first reported in the year 1877 by Sir James Paget. James Paget was born in 1814 in Yarmouth, England he apprenticed out to a local surgeon in 1830.

In 1836, after studying medicine in London, Paget passed the examination of the Royal College of Surgeons. Paget joined the teaching and clinical staff at St, Bartholomew’s Hospital in London.

In 1854, James Paget described the first carpal tunnel syndrome as a median nerve compression following a fracture of the distal radius.

He is best remembered today for his description of the diseases which became known as Paget’s disease. 

In 1876, he read a necropsy report ‘On a form of chronic inflammation of the bones’ before the Royal Medio-Chirurgical Society and subsequently published what he believed to be the first thorough description of a disorder of bone remodeling and turnover.

It was an exhaustive and complete description of the disease; detailed postmortem findings with result of microscopical examinations of the diseased bones were given.
Sir James Paget and Paget’s disease