The cell theory of nervous tissue was proposed by to friends, Matthias Schleiden and Theodor Schwann in 1838-1839.
But for long time, nervous tissue was considered an exception in that its architecture was thought to be non-cellular.
In 1886, William His and Alfred Florel propose ‘neuron doctrine’, suggesting that the nervous system is made up of individual cells (neurons) that communicate with each other.
In 1906 Ramon y Cajal and Golgi share Nobel Prize for the discovery that the neuron is the basic communicating unit of the nervous system. He suggested that neurons communicate with each other via specialized junctions called synapses, a term coined by Sherrington in 1897.
This hypothesis became the basis of the neuron doctrine, which states that the individual unit of the nervous system is a single neuron.
Santiago Ramon y Cajal founding the assumptions of brain science, stating that the nervous system consists of numerous nerve units (neurons), anatomically and genetically independent.
He perhaps the most important early pioneer in neuroscience, to bring out basic facts about nerve cells under the light microscope.
Cajal used a histological staining technique developed by his contemporary Camillo Golgi. Golgi found that by treating brain tissue with a silver chromate solution, a relatively small number of neurons in the brain were darkly stained.
History of Neuron
